High levels of neutralizing antibodies to RSV F protein have been shown to correlate with protection from RSV disease in infants and the elderly, and the clinical effectiveness of palivizumab and ...
Zhu and his research team first analyzed the F proteins used in the development of four existing RSV vaccines—the commercially available Arexvy, mResvia and Abrysvo, and an experimental vaccine ...
The RSV F protein is a trimer in two different forms ... Standard laboratory instrumentation and methodologies were used to analyze protein structure conformation. Size-exclusion chromatography ...
The F and G proteins are the only viral components that induce neutralizing antibodies and are the primary targets of the humoral response. RSV is a major seasonal viral respiratory pathogen in ...