Rob Lowe and Melissa Gilbert met as teenagers, but their powerful chemistry led to a turbulent romance that ended in devastating circumstances ...

John Owen also pranked his dad in front of a national audience in 2019, when he wrote disses backstage while Rob Lowe was being interviewed on "The Ellen DeGeneres Show" and shared them on screen.

FOX Rob Lowe on the season 3 premiere of 'The Floor' This is not the first time Lowe has expressed his sadness at never being crowned Sexiest Man Alive. In 2019, his son John Owen Lowe trolled him ...