Chicago's eastern boundary is formed by Lake Michigan, and the city is divided by the Chicago River into three geographic sections: the North Side, the South Side and the West Side. These sections ...

Spatial transcriptomics on human brains parsed microglial reactions to amyloid immunotherapy. Both a vaccine and a therapeutic antibody summoned these cells to plaques. Responders expressed TREM2, ...

The mural by Eric Minckley gives a sense of place and show that "this isn't a drive-through" but a destination.

The values are going down downtown. Residential is going to take on a greater share of the tax bill,” an expert says, which ...

A total lunar eclipse was visible across North America including Chicago Thursday night into Friday morning. The moon passed through the Earth’s shadow overnight, appearing to turn a rusty reddish ...

A system of possibly severe thunderstorms and damaging winds is approaching the Chicago area from the west, with the overnight hours likely seeing the most active weather.

What started as a summer-like day Friday will end with potentially severe storms as a powerful system prepares to sweep across the region, but there's a narrow window of time you'll want to make sure ...

Gov. JB Pritzker's budget proposal allocates millions of dollars to redevelop long-vacant properties in Illinois. If approved ...

Winds variable at 9 mph (14.5 kph). The overnight low will be 37 °F (2.8 °C). Partly cloudy with a high of 50 °F (10 °C). Winds variable at 8 to 10 mph (12.9 to 16.1 kph). Sunny today with a h ...

The overnight low will be 34 °F (1.1 °C). Sunny with a high of 54 °F (12.2 °C). Winds variable at 6 to 17 mph (9.7 to 27.4 kph). Sunny today with a high of 59 °F (15 °C) and a low of 46 °F ...

A majority of residents of Chicago and the surrounding suburbs commute to work by car. Here’s how police scanners, live video and social media help keep them on time.