David Montgomery (knee) is the only player missing from the active roster. The starting running back remains in limbo, with ...

San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN ...

With the exception of David Montgomery, the Lions had perfect practice attendance Saturday among players on the active roster ...

San Francisco 49ers face a daunting Week 17 test against Detroit Lions with injuries threatening their ability to compete.

It's a recipe that's as versatile as it is simple. Pair it with tortilla chips, quesadillas, tacos — whatever you want on ...

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

The 49ers are eliminated from the playoffs. But don't tell Kittle or Samuel that, with both studs having two of their best ...

Detroit Lions defensive coordinator Aaron Glenn called San Francisco 49ers TE George Kittle 'the best tight end in the game.' ...

The Lions held a 17-point lead in the NFC championship game over the San Francisco 49ers before getting outscored 27-7 in the ...

The Detroit Lions will know how meaningful their matchup with the San Francisco 49ers on Monday night will carry before they ...

This isn't the same 49ers team the Lions lined up against 11 months ago, but Detroit is still treating it like a marquee game ...