As the 49ers look to play spoiler against the Lions on Monday Night Football, RB Isaac Guerendo got a positive injury update.

Even as his Detroit Lions thrive in 2024, head coach Dan Campbell is not forgetting how last season ended. His 13-2 Lions are set to face the 6-9 ...

San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...

David Montgomery (knee) is the only player missing from the active roster. The starting running back remains in limbo, with ...

The last time Brock Purdy faced the Lions, he beat them in the NFC Championship Game. Now the Lions are coming back to town for revenge. And they're ...

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

The playoff-eliminated San Francisco 49ers are set to host the Detroit Lions on Monday night in a rematch of last season's ...

San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN ...

The Detroit Lions announced a pair of roster moves on Saturday afternoon, ahead of their Week 17 showdown against the San ...

It's a recipe that's as versatile as it is simple. Pair it with tortilla chips, quesadillas, tacos — whatever you want on ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

NFL Week 17 matchups, odds, picks and props following Christmas Day games. Three Saturday contests followed by Sunday's most ...