Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Shortly before the Starboard situation came to light, Pfizer in September pulled the centerpiece of the transaction—the sickle cell disease therapy ... Pfizer's CEO, Albert Bourla, Ph.D ...

The pharmaceutical giant named Jeffrey Legos the head of a division it is counting on to overcome investor pressure and grow ...

Some, like Pfizer Inc. Chief Executive Officer Albert Bourla, were in Washington for the inauguration weekend. And within the corporate ranks, there was optimism that the new administration would ...

Gene therapy involves the introduction of new genes into cells, to restore or add gene expression, for the purpose of treating disease. Most commonly a mutated gene is replaced with DNA encoding a ...

While the exact date of the meeting was not disclosed, Bourla said he and the health secretary nominee chatted civilly, conversing on topics they agreed on rather than straying to more divisive ...

Nanoscope Therapeutics is on the brink of filing for FDA approval of what could be the first gene therapy for incurable eye disease retinitis pigmentosa (RP) that can be used regardless of ...

Factor VIII gene was introduced into hematopoietic stem cells in men with hemophilia. The annualized bleeding rate went from 10 to 0. No worrisome gene integrations were seen. The content of this ...

The company made its debut last year with a $51 million Series A and a licensing agreement with Astellas for a gene therapy candidate (KT430) for X-linked myotubular myopathy. Shortly after that ...

Prince Albert has expressed his shock and sadness following the loss of one of his friends. The Monaco head of state, 66, shared his and Princess Charlene's condolences to the family of Didier ...

Janet Glockler-Hooke told 880 CHED she was headed to a mall in St. Albert, Alta., on Saturday and when she turned into the parking lot, she noticed three men holding signs and flags that concerned ...

Although these diseases were initially treated by transplantation of allogeneic hematopoietic stem cells, the past 20 years has shown that these conditions are correctable by gene therapy.