Double dose extracorporeal shockwave may be more effective for …
Oct 8, 2024 · 1. Double-dose ESWT to the gastrocnemius and soleus showed greater improvements in post-stroke ankle plantar flexor spasticity Evidence Rating Level: 1 (Excellent) Spasticity is a frequent complication following a stroke, resulting from upper motor neuron syndrome. It presents as an increase in muscle tone that depends on movement speed, caused by heightened excitability of muscle
Pomalidomide effective in reducing epistaxis in hereditary …
Oct 11, 2024 · 1. Among patients with hereditary hemorrhagic telangiectasia (HHT), pomalidomide significantly reduced the severity of epistaxis and improved quality of life. 2. Pomalidomide was associated with neutropenia, constipation, and rash. Evidence Rating Level: 1 (Excellent) Study Rundown: HHT is a common inheritable bleeding disorder characterized by fragile telangiectasias and arteriovenous ...
Semaglutide reduces heart failure events in patients with …
Sep 24, 2024 · 1. Patients in the semaglutide group reported fewer heart failure events than those in the placebo group. 2. No significant difference was observed between groups for cardiovascular death alone. Evidence Rating Level: 1 (Excellent) Study Rundown: Heart failure with preserved ejection fraction (HFpEF) is the most common form of heart failure, affecting patients with obesity,
Landmark Trials & Summaries: The Classics in Medicine - 2 Minute …
A deep understanding of these trials is paramount for every physician, healthcare professional, and trainee, as it lays the foundation for evidence-based clinical decisions made daily. 2MM+ Subscriber Exclusive Access: The Online Edition of The Classics Series™ includes The Classics in Medicine™ textbook and all deep-dive sub-specialty ...
Patient Basics: Epiglottitis - 2 Minute Medicine
Nov 30, 2014 · Epiglottitis is a rare, but potentially life-threatening infection. It causes sudden swelling of the epiglottis, which often worsens rapidly, sometimes within hours. Without timely treatment, the epiglottis can become so large that it blocks the windpipe, making it hard to breathe. This can cause death. Epiglottitis can occur at any age.
Body roundness index may help estimate cardiovascular disease
Oct 5, 2024 · 1. A higher body roundness index (BRI) trajectory is associated with an increased risk of cardiovascular disease (CVD). Evidence Rating Level: 2 (Good) The BRI, first proposed in 2013, is an index used to quantify a person’s body shape by using waist circumference and height which provides a more accurate estimation of an individual’s body fat and visceral fat composition than traditional ...
The Ultimate Guide to Achieving a Competitive MCAT Score for …
Nov 28, 2023 · Welcome to the ultimate guide that will help you achieve a competitive MCAT score for your medical school admissions. The MCAT (Medical College Admission Test) is a comprehensive examination that plays a crucial role in the medical school application process.
Weekly insulin efsitora alfa is non-inferior to daily insulin degludec ...
Oct 9, 2024 · In-depth [randomized-controlled trial]: Between Aug 12, 2022, and May 7, 2024, 893 patients were assessed for eligibility across 82 centers in 6 countries. Included were patients ≥ 18 years with type 1 diabetes and HbA1c between 7.0-10.0%. Altogether, 692 patients (343 in once weekly efsitora group and 349 in once daily degludec group) were included in the final analysis.
Tirzepatide reduces obstructive sleep apnea symptoms and …
Oct 10, 2024 · 1. In this randomized controlled trial, in patients with both moderate-severe obstructive sleep apnea (OSA) and obesity, it was found that tirzepatide treatment reduced the occurrence of apneas and hypopneas. 2. Tirzepatide treatment was associated with reduced body weight and sleep apnea-associated cardiovascular risk factors. Evidence Rating Level: 1 (Excellent) Study Rundown: OSA, resulting ...
Endeavor BioMedicinesENV-101 (Taladegib): A Safe and Efficacious ...
Jun 12, 2024 · ENV-101 is a safe and well-tolerated, unique, disease-modifying agent in the treatment of IPF. ENV-101 not only improved lung function but also reversed signs of fibrosis in patients with IPF over 12 weeks. The Latest A randomized, double-blinded, placebo-controlled phase 2a clinical trial funded by Endeavor BioMedicines investigated the …